We have all been sad for a while in our lives, but frustration, frustration can be very deep, long lasting and more painful.

Because of this, people lose interest in their lives and the mind is distracted by daily activities.

But why the frustration?

The cause of the depression is not yet clear, but it is believed to have played a significant role in many of them.

Many important stages, such as the death of a loved one, job loss, or marriage, often lead to depression.

With them, if something bad is going to happen in your mind, there is a risk of depression. Underneath this, people are thinking, 'I have failed in everything.'

Depression also occurs in people for some medical reasons, one of which is low thyroid. Depression can also be a side effect of some medications. These include some of the medications used to lower blood pressure.

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What role does brain chemistry play in the state of depression, yet it is not fully understood. But most experts agree that this is not just due to any imbalance in the brain.

Who is frustrated?

There is a short answer - it can happen to anyone.

By the way, research suggests that there may be a genetic cause behind it. Under this, some people are more likely to get frustrated when going through challenging times.

People with a history of depression are also more likely to develop depression. In addition, some genetic mutations in chromosome 3 can also cause depression. About four percent of people are affected by this.

Role of drugs,

Anti-depressants affect the way the chemical works in the brain. But the role of these chemicals in depression is not fully understood and anti-depressants do not work for everyone.

Depression further impairs the way neurotransmitters work in the brain. These are neurons, chemical messengers that facilitate the connection between brain cells.
Messages sent by neurotransmitters are received by receptors in the next neuron. Some receptors may or may not be more sensitive to a specific neurotransmitter.

Anti-depressants gradually increase the levels of mood-altering neurotransmitters.
These include the neurotransmitters serotonin, norepinephrine and dopamine.
 Most people have to take these medicines for a few weeks and it starts to take effect.

Antidepressant drugs were first developed in the 1950s and there are four types of antidepressants in total.
These chemicals affect the brain in some way.


A commonly used antidepressant increases serotonin levels in the brain. In addition, serotonin and noradrenaline re-take inhibitors are new antidepressants that target SNRI norepinephrine.


what is depression in english?


Tricyclic antidepressants and monoamine-oxidase inhibitors are chronic anti-depressants and are not commonly used because they also have site effects.

Anti-depressants relieve some of the symptoms of depression but they do not affect its root cause. Therefore do not use them alone with other treatments.

Most people experience depression or frustration at times. It is a common reaction to loss of life or struggle.

Severe sadness - when you feel helpless, helpless and useless - lasts from several days to weeks and prevents you from living your life, which is more than sadness.
 You may have a clinical medical condition - clinical depression.

How do I know if I have depression?

According to DSM-5, using a manual doctor to diagnose mental disorders, you will be disappointed when you have five or more symptoms for at least 2 weeks:
1.During the day, especially in the morning
2.You feel tired or lack of energy almost every day.
3.You feel useless or guilty almost every day.
4.It is very difficult for you to focus, remember the details and make decisions.
5.You can’t sleep or you sleep too much every day.
6.Almost every day you have no interest or pleasure in many activities.
7.You often think of death or suicide (not just the fear of death).
8.You may feel fickle or slow.
9.Have you lost or gained weight.
You too:
1.Feeling irritated and fickle
2.Lose joy in life
3.More hungry or stopped
4.Pain or aches, headaches, cramps or digestive problems go away or are not cured with treatment
5.Have sad, anxious or “empty” feelings
While these symptoms are common, they are not the same for all people with depression. 
Your features may also be in the sample. For example, depression may be accompanied by a change in the environment (formerly known as a seasonal affection disorder).

what is depression in english?

Can Depression Have Physical Symptoms?
It is not uncommon for people to suffer from depression

Signs of the situation. Among them are joint pains, back pain,

 Digestive problems, sleep disturbance and changes in appetite. You probably are

 Slowed speech and movements. Cause

That brain chemistry is associated with depression, especially serotonin and

 Norepinephrine plays a role in both mood and pain




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